Antibiotic Pollution: The Threat We Are Not Aware Of

Ugur Comlekcioglu (PhD)
5 min readNov 27, 2024

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Antibiotic Pollution Threatens Our Future

One of the greatest discoveries of modern medicine is antibiotics. Antibiotics have played an important role in saving countless lives, controlling infections and increasing agricultural productivity. However, by misusing and overusing these beneficial drugs, we have caused a new crisis that threatens not only our health systems but also our environment and our future: antibiotic pollution.

The European Centre for Disease Prevention and Control estimates that 25,000 people die each year in Europe directly from drug-resistant bacterial infections. Furthermore, estimates provided by the British government suggest that around half a million people die worldwide. Antibiotic resistance also poses a significant financial burden to global economies, with an estimated $35 billion spent annually in the US alone on treating resistant infections. Worse still, the rate of antibiotic discovery has slowed in recent years due to technical and economic difficulties, leading to an “antibiotic crisis”.

A significant part of antibiotics given to animals or humans are not fully absorbed by the body, and unfortunately they are excreted into the environment. These residues accumulate in water sources, soil and even plant systems, resulting the development of antibiotic-resistant bacteria (ARB). These bacteria have a serious risk to public health by rendering previously treatable infections difficult or impossible to cure.

Antibiotic pollution is not only an environmental issue. It is also an economic and social crisis. It effects industries ranging from aquaculture to agriculture and endangers both ecosystems and human health. Fortunately, scientists and other environmentally concerned individuals are now finding alternatives to reduce this addiction to antibiotics. People are now seeking new ways of dealing with the already emitted pollutants. This is so important because our commitment today to solve this problem secures a brighter, more sustainable world tomorrow.

Alternatives to Antibiotics

Several alternative approaches have been suggested by Yang and colleagues to mitigate the environmental impacts of antibiotics. These suggestions would not only protect the environment but also support animal health:

1. Enzymes: Enzymes added to animal feed can improve digestion and reduce the need for antibiotics. For example, proteases and amylases have been shown to increase nutrient absorption in the intestines, boost immunity and reduce the risk of infection.
2. Probiotics: Probiotics are beneficial microorganisms that regulate intestinal flora and strengthen the immune system in animals. Strains such as Lactobacillus and Bifidobacterium form a protective barrier in the intestines, preventing infections and promoting good health.
3. Plant Extracts: Natural compounds derived from plants such as oregano, turmeric and ginger have strong antimicrobial and immune-boosting properties. For example, oregano oil has been shown to be effective as a natural antibiotic.
4. Oligosaccharides: These are short-chain carbohydrates that provide nutrients to beneficial intestinal bacteria and support their growth. For example, mannan oligosaccharides have been shown to prevent harmful pathogens from adhering to the intestinal lining.
5. Organic Acids: Naturally occurring or synthetic organic acids reduce the pH in the gut, inhibiting the growth of harmful bacteria. Acids such as formic and citric acids are widely used in animal feed as effective antibiotic alternatives.
6. Antimicrobial Peptides: Found in the natural immune system of animals, they provide strong antibacterial properties. Peptides such as melittin and defensins target harmful bacteria while supporting intestinal health.

Cleaning up antibiotic pollution

Yang and colleagues addressed innovative and effective solutions to current antibiotic pollution. Four methods are proposed below:

1. Biochar Adsorption Technology: Biochar obtained from agricultural waste can effectively remove antibiotic residues from soil and water. Its high surface area and porous structure limit the mobility and bioavailability of antibiotics in the environment.
2. Advanced Oxidation Technologies: Strong oxidative agents such as hydroxyl radicals chemically break down antibiotic residues. For example, combining UV light and ozone can effectively remove antibiotics from water and soil.
3. Phytoremediation (Plant-Based Cleaning): Certain plants can be used to adsorb or break down antibiotic residues from soil and water. Plants such as duckweed and reed have been proven effective in treating contaminated water.
4. Microbial Degradation Technology: Soil microorganisms break down antibiotics into harmless substances. Bacteria such as Bacillus and Pseudomonas play an important role in breaking down pollutants and restoring ecological balance.

Protecting the health and environment together

Environmental challenges are becoming increasingly complex, and antibiotic pollution seriously threatens both human and ecosystem health, however, there is hope. Solutions inspired from nature proposed by Yang and colleagues offer promising alternatives to antibiotics, while innovative remediation technologies tackle accumulated residues.

Although antibiotic contamination has been detected in the environments studied, most of these studies have so far been largely in North America, Europe and China. Therefore, more studies are needed from Africa, South America, Oceania and Asia to better capture the current problem of antibiotic contamination. Furthermore, the development of a database of antibiotic contamination in different climates would help develop strategies needed to reduce the risk of antibiotic contamination.

Biochar, advanced oxidation technologies, phytoremediation, and microbial degradation methods provide effective ways to clean up antibiotic pollution without harming nature. At the same time, natural alternatives like probiotics, enzymes, and plant extracts protect the environment and animal health.

Solving this problem depends not only on science and technology but also on raising public awareness. Ecological agriculture and animal husbandry policies should be implemented and consumers should make more conscious choices. The fight against antibiotic pollution is a common task for everyone, not just scientists or environmentalists.

Let us remember that every living being on this planet is part of an intricate chain. We have to protect this chain to create a livable world. A healthier environment will be the most valuable legacy we will leave to future generations. Let’s not forget that it is our responsibility to work for a cleaner, healthier and safer planet.

References:

Yang, W., Li, J., Yao, Z., & Li, M. (2024). A review on the alternatives to antibiotics and the treatment of antibiotic pollution: Current development and future prospects. Science of The Total Environment, 171757.

Kraemer, S. A., Ramachandran, A., & Perron, G. G. (2019). Antibiotic pollution in the environment: from microbial ecology to public policy. Microorganisms, 7(6), 180.

Gothwal, R., & Shashidhar, T. (2015). Antibiotic pollution in the environment: a review. Clean–Soil, Air, Water, 43(4), 479–489.

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Ugur Comlekcioglu (PhD)
Ugur Comlekcioglu (PhD)

Written by Ugur Comlekcioglu (PhD)

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